PHASE3
A weekly podcast exploring medicine 4.0 as we launch into the 21st Century of health. Join us as we highlight the science and investment case for the different diseases and conditions that life sciences companies are trying to diagnose and cure.
Episodes
16 episodes
VAXXED: And the winner is... with OneVentures and Ose Immunotherapeutics
Moderna and BioNTech are getting all of the attention with their phase 3 clinical trials for lung cancer and melanoma. But someone else is already further ahead. French company Ose Immunotherapeutics has already done a phase...
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Season 3
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Episode 5
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27:32
VAXXED: Game on, with BASE and WEHI
Cancer vaccines are an area that anyone who is anyone is getting into, but it's a field led largely by academics, not-for–profits, and specialist researchers. So this week we go back to basics - science that is. Australia may ...
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Season 3
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Episode 4
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26:07
VAXXED: Boom or bust? With Chris Kallos and Pitt Street Research
In some ways, cancer vaccines are a history of hype and hope, over success. But that hasn't stopped people from trying. In 2024, biotech CEOs are hoping that this time, it's different. Research houses are predicting significant market g...
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Season 3
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Episode 3
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18:30
VAXXED: Deadly infection, with Imugene and ImmVirX
Cancer vaccines are a very niche section of cancer treatments. But two companies in Australia – the only two so far to go public with their work in this arena –are working on an even niche area within this. And one says their work is not a vacc...
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Season 3
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Episode 2
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23:13
VAXXED: From Gardasil to mRNA, with Dr Ian Frazer and Wilsons Advisory
Cancer vaccines started out as prevention. Think Gardasil for cervical and oral cancers caused by HPV, and the hepatitis B vaccine for liver cancer.But today the science has moved on, to therapy vaccines. Vaccines that take immune cells...
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Season 3
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Episode 1
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28:39
NUKED: Our nuclear future, with Novartis, Wilsons Advisory and Cyclotek
Drone-deliveries of radioactive medicines and diagnostics to Australia's far-flung towns. Radiopharmaceuticals matched with genetic information to tailor precisely the right dose and isotope to a person's cancer. Pan-cancer drugs that fix many ...
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Season 2
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Episode 6
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34:16
NUKED: Patent puzzles, with FB Rice
The rule of thumb in biotech is that it costs around $1 billion to bring a new therapy from lab to market. Protecting that investment is the patent system. But what if part of your product is not made by your contract manufacturer, but by the p...
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Season 2
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Episode 5
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25:20
NUKED: Australia the nuclear power, with entX and Cyclowest
Can Australia create a mine to lab to bedside production line for radiopharmaceutical medicine? It has the reactor, biotechs and the hospitals to do that last two, and even has a growing pool of expertise to run these. What it doesn...
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Season 2
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Episode 4
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29:58
NUKED: The IP game, with Clarity Pharmaceuticals and Radiopharm Theranostics
The question we are dancing around in episode 3 of NUKED is whether locking down isotopes supply chains are really the only way to play the radiopharmaceutical game. We ask Clarity Pharmaceutical executive chair Alan Taylor and <...
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Season 2
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Episode 3
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26:25
NUKED: Access is everything, with GlyTherix and Telix Pharmaceuticals
In early 2023, one of the first two really big radiopharmaceutical drugs ran into a problem. Novartis' prostate cancer therapy Pluvicto, released only the year before, was suddenly in short supply, snarling up just in time treatment sched...
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Season 2
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Episode 2
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29:47
NUKED: Why radiopharmaceuticals are exploding, with Peter MacCallum Cancer Centre and HB Biotechnology
The radiopharmaceuticals sector is on a knife point. The scope of what nuclear medicine can do is exploding. But the radioisotopes that biotechs need to make those therapies are in very, very short supply. Major clinical trials are hitting paus...
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Season 2
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Episode 1
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25:34
The Silent Killer: The sci-fi episode, with Certa Therapeutics and University of Sydney CTC
Wearable kidneys. Organs on a chip. Xenotransplantation. The future is here.But is that the future people in biotech are truly looking to? Because the future that Certa Therapeutics CEO Darren Kelly is looking to is much less 1980s sci-...
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Season 1
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Episode 4
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27:59
The Silent Killer: Prevention is the next cure, with Kidney Health Australia and Proteomics International
We may have led you on a bit in the first two episodes... kidney disease is still a big problem despite the massive shifts forward in treating it. There is a long way to go to bring medical sectors -- and governments -- along as well. ...
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Season 1
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Episode 3
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23:06
The Silent Killer: Who has the killer apps? With Dimerix and PYC Therapeutics
We speak to Dimerix CEO Dr Nina Webster about why investors are thrilled with her company, as it nears the midway point for its Phase III clinical trial for the rare disease focal segmental glomerulosclerosis (FSGS).And we talk to PYC T...
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Season 1
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Episode 2
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24:40
The Silent Killer: Why biotechs are all in on kidney disease, with University of Sydney CTC and Chris Kallos
Kidney disease is a silent killer, with only 10% of all people knowing they have it before damage has been done. But in the last five years there's been a surge of work that's resulted in the FDA approving some blockbuster drugs in...
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Season 1
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Episode 1
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26:54